Publikationer
Publication list Anne Thorup, Feb 2017
Submitted:
*Thorup A, Laursen, TM, Munk-Olsen, T, Ranning A, Mortensen PB, Plessen K, Nordentoft M ' Incidence of child and adolescent mental illness in children aged 0-17 with familial high risk for severe mental illness – a Danish Register Study'
In press:
Burton BK, Thorup A.A.E., Jepsen JR, Poulsen G, Ellersgaard D, Spang KS, Christiani CJ, Hemager N, Gantriis D, Greve A, Mors O, Nordentoft M, Plessen KJ (2016) Impairments of Motor Function among Children with a Familial Risk of Schizophrenia or Bipolar Disorder at 7 Years Old – an observational cohort study. Lancet Psychiatry (in press)
2016
Ranning A, Munk LT, Thorup A, et al. Children of Parents With Serious Mental Illness: With Whom Do They Grow Up? A Prospective, Population-Based Study. J Am Acad Child Adolesc Psychiatry 2016;55:953-61
Kuhl JO, Laursen TM, Thorup A, Nordentoft M. The incidence of schizophrenia and schizophrenia spectrum disorders in Denmark in the period 2000-2012. A register-based study. Schizophr.Res. 2016;
Burton BK, Hjorthoj C, Jepsen JR, Thorup A, Nordentoft M, Plessen KJ. Research Review: Do motor deficits during development represent an endophenotype for schizophrenia? A meta-analysis. J. Child Psychol.
Psychiatry 2016; 57:446-456
2015
Melau M, Harder S, Jeppesen P, Hjorthoj C, Jepsen JR, Thorup A, Nordentoft M. The association between working alliance and clinical and functional outcome in a cohort of 400 patients with first-episode psychosis: a cross-sectional study. J.Clin.Psychiatry 2015; 76:e83-e90
*Thorup AA, Jepsen JR, Ellersgaard DV, Burton BK, Christiani CJ, Hemager N, Skjaerbaek M, Ranning A, Spang KS, Gantriis DL, Greve AN, Zahle KK, Mors O, Plessen KJ, Nordentoft M. The Danish High Risk and Resilience Study - VIA 7 - a cohort study of 520 7-year-old children born of parents diagnosed with either schizophrenia, bipolar disorder or neither of these two mental disorders. BMC.Psychiatry 2015; 15:233
Nordentoft M, Melau M, Iversen T, Petersen L, Jeppesen P, Thorup A, Bertelsen M, Hjorthoj CR, Hastrup LH, Jorgensen P. From research to practice: how OPUS treatment was accepted and implemented throughout Denmark. Early Interv.Psychiatry 2015; 9:156-162
Austin SF, Mors O, Budtz-Jorgensen E, Secher RG, Hjorthoj CR, Bertelsen M, Jeppesen P, Petersen L, Thorup A, Nordentoft M. Long-term trajectories of positive and negative symptoms in first episode psychosis: A 10year follow-up study in the OPUS cohort. Schizophr.Res. 2015;
Burton BK, Hjorthoj C, Jepsen JR, Thorup A, Nordentoft M, Plessen KJ. Research Review: Do motor deficits during development represent an endophenotype for schizophrenia? A meta-analysis. J.Child Psychol.Psychiatry 2015;
Ranning A, Munk LT, Thorup A, Hjorthoj C, Nordentoft M. Serious mental illness and disrupted caregiving for children: a nationwide, register-based cohort study. J.Clin.Psychiatry 2015; 76:e1006-e1014
Secher RG, Hjorthoj CR, Austin SF, Thorup A, Jeppesen P, Mors O, Nordentoft M. Ten-year follow-up of the OPUS specialized early intervention trial for patients with a first episode of psychosis. Schizophr.Bull. 2015; 41:617-626
2014
Clausen L, Hjorthoj CR, Thorup A, Jeppesen P, Petersen L, Bertelsen M, Nordentoft M. Change in cannabis use, clinical symptoms and social functioning among patients with first-episode psychosis: a 5-year follow-up study of patients in the OPUS trial. Psychol.Med. 2014; 44:117-126
*Thorup A, Albert N, Bertelsen M, Petersen L, Jeppesen P, Le QP, Krarup G, Jorgensen P, Nordentoft M. Gender differences in first-episode psychosis at 5-year follow-up--two different courses of disease? Results from the OPUS study at 5-year follow-up. Eur.Psychiatry 2014; 29:44-51
Nordentoft M, Rasmussen JO, Melau M, Hjorthoj CR, Thorup AA. How successful are first episode programs? A review of the evidence for specialized assertive early intervention. Curr.Opin.Psychiatry 2014; 27:167-172
Ellersgaard D, Mors O, Thorup A, Jorgensen P, Jeppesen P, Nordentoft M. Prospective study of the course of delusional themes in first-episode non-affective psychosis. Early Interv.Psychiatry 2014; 8:340-347
2013
Hastrup LH, Kronborg C, Bertelsen M, Jeppesen P, Jorgensen P, Petersen L, Thorup A, Simonsen E, Nordentoft
M. Cost-effectiveness of early intervention in first-episode psychosis: economic evaluation of a randomised controlled trial (the OPUS study). Br.J.Psychiatry 2013; 202:35-41
Nordentoft M, Melau M, Iversen T, Petersen L, Jeppesen P, Thorup A, Bertelsen M, Hjorthoj CR, Hastrup LH, Jorgensen P. From research to practice: how OPUS treatment was accepted and implemented throughout Denmark. Early Interv.Psychiatry 2013;
Austin SF, Mors O, Secher RG, Hjorthoj CR, Albert N, Bertelsen M, Jensen H, Jeppesen P, Petersen L, Randers L, Thorup A, Nordentoft M. Predictors of recovery in first episode psychosis: the OPUS cohort at 10 year follow- up. Schizophr.Res. 2013; 150:163-168
2011
Melau M, Jeppesen P, Thorup A, Bertelsen M, Petersen L, Gluud C, Krarup G, Nordentoft M. The effect of five years versus two years of specialised assertive intervention for first episode psychosis - OPUS II: study protocol for a randomized controlled trial. Trials 2011; 12:72
Albert N, Bertelsen M, Thorup A, Petersen L, Jeppesen P, Le Quack P, Krarup G, Jorgensen P, Nordentoft M. Predictors of recovery from psychosis Analyses of clinical and social factors associated with recovery among patients with first-episode psychosis after 5years. Schizophr.Res. 2011; 125:257-266
2010
Nordentoft M, Ohlenschlaeger J, Thorup A, Petersen L, Jeppesen P, Bertelsen M. Deinstitutionalization revisited: a 5-year follow-up of a randomized clinical trial of hospital-based rehabilitation versus specialized assertive intervention (OPUS) versus standard treatment for patients with first-episode schizophrenia spectrum disorders. Psychol.Med. 2010; 40:1619-1626
*Thorup A, Petersen L, Jeppesen P, Nordentoft M. The quality of life among first-episode psychotic patients in the OPUS trial. Schizophr.Res. 2010; 116:27-34
2009
Bertelsen M, Jeppesen P, Petersen L, Thorup A, Ohlenschlaeger J, Le Quach P, Ostergaard CT, Krarup G, Jorgensen P, Nordentoft M. Course of illness in a sample of 265 patients with first-episode psychosis--five-year follow-up of the Danish OPUS trial. Schizophr.Res. 2009; 107:173-178
Bertelsen M, Jeppesen P, Petersen L, Thorup A, Ohlenschlaeger J, Le Quach P, Christensen TO, Krarup G, Jorgensen P, Nordentoft M. [First episode of psychosis intensive early intervention programme versus standard treatment--secondary publication]. Ugeskr.Laeger 2009; 171:2992-2995
Quach PL, Mors O, Christensen TO, Krarup G, Jorgensen P, Bertelsen M, Jeppesen P, Petersen L, Thorup A, Nordentoft M. Predictors of poor adherence to medication among patients with first-episode schizophrenia- spectrum disorder. Early Interv.Psychiatry 2009; 3:66-74
Nordentoft M, Jeppesen P, Petersen L, Bertelsen M, Thorup A. The rationale for early intervention in schizophrenia and related disorders. Early Interv.Psychiatry 2009; 3 Suppl 1:S3-S7
2008
Jeppesen P, Petersen L, Thorup A, Abel MB, Ohlenschlaeger J, Christensen TO, Krarup G, Jorgensen P, Nordentoft M. The association between pre-morbid adjustment, duration of untreated psychosis and outcome in first-episode psychosis. Psychol.Med. 2008; 38:1157-1166
Nordentoft M, Larsen T, Bertelsen M, Thorup A. The challenge of suicidal behaviour in early psychosis. Early Interv.Psychiatry 2008; 2:1-2
Nordentoft M, Thorup A, Petersen L, Ohlenschlaeger J, Christensen TO, Krarup G, Jorgensen P, Jeppesen P. Does a detection team shorten duration of untreated psychosis? Early Interv.Psychiatry 2008; 2:22-26
Ohlenschlaeger J, Nordentoft M, Thorup A, Jeppesen P, Petersen L, Christensen TO, Krarup G, Jorgensen P. Effect of integrated treatment on the use of coercive measures in first-episode schizophrenia-spectrum disorder. A randomized clinical trial. Int.J.Law Psychiatry 2008; 31:72-76
Bertelsen M, Jeppesen P, Petersen L, Thorup A, Ohlenschlaeger J, Le Quach P, Christensen TO, Krarup G, Jorgensen P, Nordentoft M. Five-year follow-up of a randomized multicenter trial of intensive early intervention vs standard treatment for patients with a first episode of psychotic illness: the OPUS trial. Arch.Gen.Psychiatry 2008; 65:762-771
Nordentoft M, Bertelsen M, Petersen L, Jeppesen P, Thorup A. [Phases of psychosis]. Ugeskr.Laeger 2008; 170:3746-3748
Petersen L, Thorup A, Oqhlenschlaeger J, Christensen TO, Jeppesen P, Krarup G, Jorrgensen P, Mortensen EL, Nordentoft M. Predictors of remission and recovery in a first-episode schizophrenia spectrum disorder sample: 2-year follow-up of the OPUS trial. Can.J.Psychiatry 2008; 53:660-670
2007
*Thorup A, Petersen L, Jeppesen P, Nordentoft M. Frequency and predictive values of first rank symptoms at baseline among 362 young adult patients with first-episode schizophrenia Results from the Danish OPUS study. Schizophr.Res. 2007;
*Thorup A, Petersen L, Jeppesen P, Ohlenschlaeger J, Christensen T, Krarup G, Jorgensen P, Nordentoft M. Gender differences in young adults with first-episode schizophrenia spectrum disorders at baseline in the Danish OPUS study. J.Nerv.Ment.Dis. 2007; 195:396-405
Ohlenschlaeger J, Thorup A, Petersen L, Jeppesen P, Koster A, Munkner R, Nordentoft M. Intensive treatment models and coercion. Nord.J.Psychiatry 2007; 61:369-378
Petersen L, Jeppesen P, Thorup A, Ohlenschlaeger J, Krarup G, Ostergard T, Jorgensen P, Nordentoft M. Substance abuse and first-episode schizophrenia-spectrum disorders. The Danish OPUS trial. Early Interv.Psychiatry 2007; 1:88-96
Bertelsen M, Jeppesen P, Petersen L, Thorup A, Ohlenschlaeger J, Le Quach P, Christensen TO, Krarup G, Jorgensen P, Nordentoft M. Suicidal behaviour and mortality in first-episode psychosis: the OPUS trial. Br.J.Psychiatry Suppl 2007; 51:s140-s146
*Thorup A, Waltoft BL, Pedersen CB, Mortensen PB, Nordentoft M. Young males have a higher risk of developing schizophrenia: a Danish register study. Psychol.Med. 2007; 37:479-484
2006
Nordentoft M, Petersen L, Jeppesen P, Thorup AA, Abel MB, Ohlenschlaeger J, Christensen TO, Krarup G, Jorgensen P. [OPUS: a randomised multicenter trial of integrated versus standard treatment for patients with a first-episode psychosis--secondary publication]. Ugeskr.Laeger 2006; 168:381-384
*Thorup A, Petersen L, Jeppesen P, Ohlenschlaeger J, Christensen T, Krarup G, Jorgensen P, Nordentoft M. Social network among young adults with first-episode schizophrenia spectrum disorders: results from the Danish OPUS trial. Soc.Psychiatry Psychiatr.Epidemiol. 2006; 41:761-770
Nordentoft M, Thorup A, Petersen L, Ohlenschlaeger J, Melau M, Christensen TO, Krarup G, Jorgensen P, Jeppesen P. Transition rates from schizotypal disorder to psychotic disorder for first-contact patients included in the OPUS trial. A randomized clinical trial of integrated treatment and standard treatment. Schizophr.Res. 2006; 83:29-40
2005
Petersen L, Nordentoft M, Jeppesen P, Ohlenschaeger J, Thorup A, Christensen TO, Krarup G, Dahlstrom J, Haastrup B, Jorgensen P. Improving 1-year outcome in first-episode psychosis: OPUS trial. Br.J.Psychiatry Suppl 2005; 48:s98-103
*Thorup A, Petersen L, Jeppesen P, Ohlenschlaeger J, Christensen T, Krarup G, Jorgensen P, Nordentoft M. Integrated treatment ameliorates negative symptoms in first episode psychosis-results from the Danish OPUS trial. Schizophr.Res. 2005; 79:95-105
Jeppesen P, Petersen L, Thorup A, Abel MB, Oehlenschlaeger J, Christensen TO, Krarup G, Hemmingsen R, Jorgensen P, Nordentoft M. Integrated treatment of first-episode psychosis: effect of treatment on family burden: OPUS trial. Br.J.Psychiatry Suppl 2005; 48:s85-s90
Petersen L, Jeppesen P, Thorup A, Abel MB, Ohlenschlaeger J, Christensen TO, Krarup G, Jorgensen P, Nordentoft M. A randomised multicentre trial of integrated versus standard treatment for patients with a first episode of psychotic illness. BMJ 2005; 331:602
Reference List
1. Ranning A, Munk LT, Thorup A, et al. Children of Parents With Serious Mental Illness: With Whom Do They Grow Up? A Prospective, Population-Based Study. J Am Acad Child Adolesc Psychiatry 2016;55:953- 61