​​The Neurocognition and Emotion in Affective Disorders (NEAD) Group works on research in depression and bipolar disorder (mania and depression) and aims to:
  1. Identify neurocognitive and neuroimaging biomarkers of these affective disorders
  2. Develop new biological and psychological treatments targeting cognitive dysfunction across the disorders and
  3. Delineate the neurocognitive and neuroimaging mechanisms of established and novel treatments.

Identification of neurocognitive and neuroimaging biomarkers of affective disorders

Using functional magnetic resonance imaging (fMRI) study of healthy monozygotic twins at high vs. low heritable risk for depression, we showed that familial risk was associated with aberrant functional connectivity in...read more 

​Devel​o​pment of novel treatments targeting cognitive dysfunction

​Cognitive dysfunction in attention, memory and executive function occurs across a range of neuropsychiatric disorders including depression and bipolar disorder and is an emerging common therapeutic target. However, there is...read more

Exploring neurocognitive​ and neuroimaging mechanisms of established and novel treatments

Using prospective MRI in the EPO trials, we demonstrated that EPO-treatment prevented subfield hippocampal volume loss across both unipolar and bipolar disorder and that this structural change mediated...read more​​