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Neuropsykiatrisk Laboratorium

Neuropsykiatrisk Laboratorium er Psykiatrisk Center Københavns forskningslaboratorium, og er også en del af Københavns Universitet. Laboratoriet blev grundlagt i 1898 og har siden 1934 været beliggende ved Rigshospitalets psykiatriske afdeling. Laboratoriet ledes af en styringsgruppe bestående af Anders Fink-Jensen, Gitta Wörtwein og Morgane Thomsen.

 

The Laboratory of Neuropsychiatry is the research laboratory of Psychiatric Center Copenhagen, and is also part of the University of Copenhagen. The laboratory was founded in 1898 and has been located at the psychiatric department at Rigshospitalet (Copenhagen University Hospital) since 1934. The laboratory is headed by a steering group consisting of Anders Fink-Jensen, Gitta Wörtwein, and Morgane Thomsen.

Primære forskningsområder

Vi er et translationelt laboratorie, hvor vi laver både kliniske studier og grundforskning. Vi undersøger de biologiske mekanismer, der ligger til grund for psykiatriske lidelser, med henblik på af finde og afprøve nye behandlinger. Primære forskningslinier i laboratoriet fokuserer på afhængighed af euforiserende stoffer og alkohol, specifikt det Glucagon-lignende peptid-1-system, ketogener diæter, og det muskarine kolinerge system; psykose med særlig vægt på samspillet mellem det muskarine kolinerge og det dopaminerge transmittersystem; bivirkninger af antipsykotika og lindring/forebyggelse af disse.

 

MAIN RESEARCH AREAS

We are a translational laboratory conducting both clinical and basic research studies. We investigate the biological mechanisms underlying psychiatric disorders with the goal of identifying and testing new treatments. Principal lines of investigation in the laboratory focus on drug and alcohol addiction, specifically the Glucagon-like peptide-1 system, ketogenic diets, and the muscarinic cholinergic system; psychosis with special emphasis on the interaction between the muscarinic and the dopaminergic transmitter system; adverse effects of antipsychotic treatments and how to ameliorate or prevent these.

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St​​aff

Professor, MD PhD, Anders Fink-Jensen

Senior researcher, Associate professor, PhD, Morgane Thomsen

Associate professor, PhD, Gitta Wörtwein

Postdocoral researcher, MD PhD, Mette K. Klausen

Postdocoral researcher, MD PhD, Cesar R. R. Leguizamon

PhD candidate, MSc, Abhishek Shankar Balakrishnan

PhD candidate, MSc, Anna Berezovskaia

PhD candidate, MD, Mathias Ebbesen Jensen

PhD candidate, MD, Daniel Thaysen Petersen

PhD candidate, MD, Marie Reeberg Sass

PhD candidate, MSc, Simone Tonetto

PhD candidate, MD, Anne-Cathrine Vissing

Master's thesis students (changing annually)

Medical students ("skolar", changing annually)

Research assistant Veronika H. S. Bonnevie

Research assistant Maria Kyriakidou

Laboratory technician Anne-Marie Paulsen

Laboratory technician Saiye Kiasari

Secretary Astrid Tanja Brundbjerg

COLLABO​RATIONS

We maintain research collaborations with laboratories in Denmark and internationally, including:

 

  • Psychiatric Centre Copenhagen, Rigshospitalet: Professor Martin Balslev Jørgensen, Professor Kamilla Woznica Miskowiak, Head of Clinic Ida Hageman, Professor Lars Vedel Kessing, Professor Klaus Martiny, Senior consultant Anders Jørgensen
  • Professor Gitte Moos Knudsen, Neurobiology Research Unit, Region Hovedstaden Rigshospitalet, and Professor Tina Vilsbøll, Region Hovedstaden Steno Diabetes Center Copenhagen
  • Drs. Susana Aznar Klejn, Mikkel Vestergaard Olesen, and Tomasz Brudek, Center for Neuroscience and Neurostereology, Region Hovedstaden Bispebjerg University Hospital.
  • Professor Maiken Nedergaard and Senior researcher Pia Weikop, Center for Translational Neuromedicine, University of Copenhagen
  • Associate Professor Barak Caine, Neuroscience and Behavioral Pharmacology Laboratory, McLean Hospital, Harvard Medical School, USA.
  • Drs. Nora Volkow, Leandro Vendruscolo, and George F. Koob, National Institute on Drug Abuse intramural research program, USA
  • Professors Graeme Mason and Helene Benveniste, Yale School of Medicine
  • Professor Ulrik Gether, Department of Neuroscience, University of Copenhagen
  • Professor Jens Juul Holst, Department of Biomedical Sciences, University of Copenhagen
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  • Associate Professor Matthew Gillum, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen
  • Professor Martin Fredensborg Rath and Professor emeritus Morten Møller, Department of Neuroscience, University of Copenhagen
  • Associate Professors Kristi A. Kohlmeier and Jesper T. Andreasen, Drug Design and Pharmacology, University of Copenhagen
  • Associate Professor Steen Larsen, Department of Biomedical Sciences, University of Copenhagen
  • Professor Claus Thorn Ekstrøm, Section of Biostatistics, Department of Public Health, University of Copenhagen
  • Professor Craig Lindsley and Associate Professor Carrie K. Jones, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Professor S. Stevens Negus, Department of Pharmacology and Toxicology, Virginia Commonwealth, USA.
  • Professor Ann M. Graybiel and Dr. Jill Crittenden, McGovern Institute, Massachusetts Institute of Technology, USA
  • Professor Roberta Palmour, Department of Human Genetics McGill University, Montreal, Canada.
  • Drs. Robin Witt and Christine Ryan, Gabather, Sweden
  • We are part of the Copenhagen Center for Translational Research, Bispebjerg Hospital​


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Redaktør
Helene Kaspersen