Neuropsykiatrisk Laboratorium

Neuropsykiatrisk Laboratorium er Psykiatrisk Center Københavns forskningslaboratorium, og er også en del af Københavns Universitet. Laboratoriet blev grundlagt i 1898 og har siden 1934 været beliggende ved Rigshospitalets psykiatriske afdeling. Laboratoriet ledes af en styringsgruppe bestående af Anders Fink-Jensen, Gitta Wörtwein og Morgane Thomsen. 

The Laboratory of Neuropsychiatry is the research laboratory of Psychiatric Center Copenhagen, and is also part of the University of Copenhagen. The laboratory was founded in 1898 and has been located at the psychiatric department at Rigshospitalet (Copenhagen University Hospital) since 1934. The laboratory is headed by a steering group consisting of Anders Fink-Jensen, Gitta Wörtwein, and Morgane Thomsen.

Primære forskningsområder

Vi undersøger de biologiske mekanismer, der ligger til grund for psykiatriske lidelser og døgnrytmer. Primære forskningslinier i laboratoriet fokuserer på afhængighed af euforiserende stoffer og alkohol, specifikt det Glucagon-lignende peptid-1-system og det muskarine kolinerge system; psykose med særlig vægt på samspillet mellem det muskarine kolinerge og det dopaminerge transmittersystem, og døgnrytmer med særlig vægt på centrale klokkegener.

Main research areas

We investigate the biological mechanisms underlying psychiatric disorders and circadian rhythms. Principal lines of investigation in the laboratory focus on drug and alcohol addiction, specifically the Glucagon-like peptide-1 system and the muscarinic system; psychosis with special emphasis on the interaction between the muscarinic and the dopaminergic transmitter system, and circadian rhythms with special emphasis on central nervous system clock genes.

 

Collaborations

We maintain research collaborations with laboratories in Denmark and internationally, including:

 

  • Professor Maiken Nedergaard, Center for Translational Neuromedicine, University of Copenhagen
  • Associate professor Martin Fredensborg Rath and professor emeritus Morten Møller, Department of Neuroscience, University of Copenhagen http://in.ku.dk/research/rath-lab/
  • Psychiatric Centre Copenhagen, Rigshospitalet: Professor Martin Balslev Jørgensen, Professor Kamilla Woznica Miskowiak;, Head of Clinic Ida Hageman, Senior consultant Henrik Dam, Professor Lars Vedel Kessing, Senior consultant Maj Vinberg, Senior consultant Klaus Munkholm, Senior consultant Ulla Knorr, Senior consultant Klaus Martiny, and Professor emeritus Tom Bolwig.
  • Barak Caine, Director of the Neuroscience and Behavioral Pharmacology Laboratory, McLean Hospital and associate professor, Harvard Medical School, USA.
  • Professor Ulrik Gether, Department of Neuroscience, University of Copenhagen.
  • Professor Jürgen Wess, Molecular Signaling Section, National Institutes of Health, USA.
  • Professors P Jeffrey Conn and Craig Lindsley, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Professor Christopher Cowan, Medical University of South Carolina, USA.
  • Professor Henrik Enghusen Poulsen, Laboratory of Clinical Pharmacology, Rigshospitalet University Hospital, Denmark.
  • Professors Steffen Loft and Peter Møller, Department of Public Health, University of Copenhagen.
  • Professor Jann Hau, Department of Experimental Medicine, Faculty of health sciences, University of Copenhagen.
  • Professor Roberta Palmour, Department of Human Genetics McGill University, Montreal, Canada.
  • Dr. Mark Burke, Department of Anatomy, Howard University, Washington, DC USA.
  • Professor Bente Pakkenberg, Laboratory for Neurostereology, Bispebjerg University Hospital, Denmark.
  • Director Christian Felder, Eli Lilly & Co, Neuroscience, Indianapolis, Indiana.
  • Professors Aurelio Galli, University Medical Center, Nashville, TN, USA.


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