Research projects conducted at CNDR aim to improve treatment of affective disorders. Below are descriptions of current and upcoming projects.  

​The Danish ECT/MRI project

The project examines the therapetic effect, side effects and risk of recurrence in patients with depression who are being treated with electroconvulsive therapy (ECT). The project makes use of the latest MRI techniques and blood tests and aims to develop a method that predicts how individual patients respond to treatment in regards to both favourable and adverse effects. The project is scheduled for completion in 2020.

Researcher: MD Krzysztof Gbyl
Supervisor: Professor, MD Poul Videbech

"Healthy Brain" – training of cognitive disorders after depression

This PhD project is in collaboration with the company Brain+, who have developed an application for smartphones and tablets that enables training of the cognitive deficits, that many formerly depressed patients suffer from. This is done in an intelligent, user-friendly and efficient way. The projects objective is a scientific evaluation of the application’s potential.

Right now the project is on standby.
Supervisor: Professor, MD Poul Videbech

National Clinical Guideline (NCG) on difficult treatable depression

The mental health service in the Capital Region of Denmark and the Danish Psychiatric Society have been granted money from the National Board of Health for the preparation of an NCG regarding. difficult treatable depression.
Chairman: Professor, MD Poul Videbech
Project manager: Psychologist, cand. psyk. Stine Bjerrum Møller

​The Danish Neuropsychological Study of Adverse Effect of ECT (DANSECT)

The purpose is to describe the frequency of this dreaded, but probably relatively rare, side effect with memory problems and find predictors for its emergence. The perspective is that we will be better to advise the individual patient about the advantages and disadvantages of the treatment. The project is mentioned in the Government's Psychiatry Plan and is likely to be financed in connection with this. The project will start in 2019 and it is financet by the Government's SATS-funds.
Supervisor: Professor, MD Poul Videbech

Killing of infants - a forensic psychiatric examination 1992-2016

The project is made in collaboration with the Institute of Forensic Medicine, Skejby hospital. Initially, we will review the mental statements as well as the judicial council's statements for the perpetrators who have killed their child during the first year of its life. The purpose is to describe mental illness and other factors that contribute to the murder being committed in order to prevent new killings. It is the plan to make a follow-up in Danish registers in order to description the treatment, prognosis and later renewed crime.
Researcher: MD Charlotte Fergo
Supervisor: Professor, MD Poul Videbech

Project with driving simulator

The driving simulator will be used in the DANSECT project to test how the cognitive function of research patients is. In addition, the plan is that it also will be used to test how much mental illness and psychopharmacological treatment affect cognitive function.

Research assistent: Jonas Borup Larsen
Supervisor: Professor, MD Poul Videbech

CNDR will collaborate with Foulum in a 4-year project concerning use of therapy animals. The project consists of two parts, with CNDR participating in the second part, consisting of two case studies - one with nursing home residents and one with war veterans. CNDR participates in the case study on war veterans, where they will examine the effect of a service dog's presence on war veterans with PTSD - both in challenging and non-challenging situations - ie. with high and low stress loads. The project is funded by the Trygfonden.

Researcher: Professor, cand.psyk. Lene Vase
Researcher: Professor, MD Poul Videbech
​Study on the prevalence of dementia after Electro Convulsive Therapy (ECT)

This registry study is made in collaboration with psychiatrist PhD Simon Hjerrild from Dept. Q at Aarhus University Hospital, Skejby. The project also examines whether ECT increases the frequency of other serious physical diseases.

Resarcher: PhD, MD Simon Hjerrild
Supervisor: Professor, MD Poul Videbech

A study of postpartum depression in the Faroe Islands

PhD student Anna Sofia Fjallheim from the University of the Faroe Islands examines the occurrence of postpartum depression in the Faroe Islands and the validity of the Edinburgh Postnatal Depression Scale.
Researcher: Nurse Anne Sofia Fjallheim
Supervisor: Professor, MD Poul Videbech

​Metabolic and transcriptomic profiling of women with postpartum depression

The PhD project is carried out in collaboration with Statens Serum Institut and examines genetic, hormonal and metabolic markers of the development of postpartum depression.
Researcher: Cand.scient.san.publ. Marie-Louise Hee Rasmussen
Supervisor: Professor, MD Poul Videbech

Neurobiological effects of work-related adjustment disorder

The purpose of this project is to identify neurobiological changes in the dopaminergic binding potential of the human brain's reward system and their possible correlation with the psychological symptom anhedonia, defined as a common symptom of depression, anxiety and stress. The study population is patients from the Department of Occupational Health, Odense University Hospital.
Researcher: M.Sc., engineer Saga Steinmann
Supervisor: Professor, MD Poul Videbech

Sleep quality and effects of ball blankets on insomnia due to depression in ambulant psychiatry

The purpose of this PhD project (PhD in Business) is to study if a Protac Ball BlanketTM is helpful as an innovative non-pharmacological alternative to the medical treatment of insomnia among out-patients with depression psychiatry.
Researcher: Cand.cur., nurse Sanne Toft Kristiansen
Supervisor: Professor, MD Poul Videbech

​Inflammation and Neuroprogression in Anorexia Nervosa

In this PhD project we want to study increased inflammation and clinical signs of neuroprogression such as impaired social cognition and loss of emotional regulation capacity in patients with anorexia. Inflammation is also associated with neurodegeneration in schizophrenia and Mood Disorders.
Researcher: MD Klara Rasmussen
Supervisor: Professor, MD Poul Videbech

Olfaction in depressed patients undergoing wake-therapy

Many studies have shown that depressed patients have reduced sense of smell. This is a Sino-Danish collaboration with the purpose to study olfactory function in depressed patients undergoing wake-therapy by clinical interview and Magneto-Encephalography (MEG). The PhD student is working part time in China and part time in Denmark.
Researcher: MSci Neuroscience Carsten Gleesborg
Supervisor: Professor, MD Poul Videbech

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