Upcoming projects

​We are currently working on starting several new research projects. You can read more about these projects below.


The Copenhagen Study of Accelerated ageing in Depression: The CPH-SAD study
This is a combined register and birth cohort-based study that investigates the influence of depression on the aging process. This includes factors such as genetic vulnerability, abnormalities of the hypothalamic–pituitary–adrenal (HPA) axis, low-grade inflammation and oxidative stress processes at the cellular level. With data from the so-called Metropolit Birth Cohort, we wish to disentangle the mechanisms behind the ageing process and elucidate their relative contributions.

 


Copenhagen study of Psychotropics during Pregnancy (COPRA)
With data from the Copenhagen Baby Heart project, this study investigates the effects of psychotropics (antidepressants, antipsychotics and mood stabilisers) taken during pregnancy. Focus is on preterm birth, heart malformations, symptoms of the neonate and passage of various psychotropics through the placenta. The information arising from the present project will make physicians better prepared to give advice as to the proper treatment in these psychiatric conditions and possible adverse effects on the baby.

 


Stress during pregnancy - how does it affect the baby?
Prenatal maternal stress affects the fetus and the future development of the child. This so-called fetal programming is involved in the pathogenesis of several diseases. However, it is still unclear what the underlying mechanisms are. This project examines if psychosocial stress during pregnancy induces epigenetic changes in the newborn or in placenta and furthermore if epigenetic changes influence the offspring stress response in the first year of life. ​



Metabolic and transcriptomic profiling of women with postnatal depression
The project is carried out in collaboration with Statens Serum Institut and examines genetic, hormonal and metabolic markers of the development of postnatal depression. The project is scheduled for completion in 2019.

Supervisor: Poul Videbech

 


"Healthy Brain" – training of cognitive disorders after depression
This project is in collaboration with the company Brain+, which has developed a customised application for smartphones and tablets that enables training the cognitive abilities of, for example, people with depression in an intelligent, user-friendly and efficient way. The project objective is a scientific evaluation of the application’s potential.

Researcher: Laura Broen Damn
Supervisor: Poul Videbech


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