Differentiation between bipolar and unipolar disorder during depressive phases represents a major clinical issue. Misdiagnosis delay has profound consequences for patients resulting in inadequate treatment and substantial impairment in socio-occupational functioning. A recent clinical discovery study identified a panel of RNA-editing blood biomarkers (which constitutes the EDIT-B test system) of patients with depression that allowed a differential diagnosis of bipolar disorder from unipolar depression. The objective of the present study is to provide an external validation of the diagnostic performances of the EDIT-B® signature on bipolar versus unipolar differentiation in patients with depression.​

For further information, please contact: Jeff Zarp Petersen
Mail: jeff.zarp.petersen@regionh.dk​