Lars Vedel Kessing, MD, DMSc
Lars Vedel Kessing is the leader of the Copenhagen Affective Disorder research Center (CADIC). He has since 2002 been appointed as professor in psychiatry at the Psychiatric Center Copenhagen and the University Hospital of Copenhagen, Denmark.
Dr. Kessing's scientific contributions are within clinical, epidemiological and neurobiological research in bipolar and unipolar affective disorders.
His major achievements has been to show that the longitudinal course of illness in depressive disorder and in bipolar disorder on average is progressive in nature with increasing severity of depressive episodes, increasing risk of recurrence of depressive and manic episodes and with increasing prevalence of cognitive dysfunction with the number of affective episodes. Further, he has shown that the risk of developing dementia is increased compared to the general population, and that the risk seems to increase with progression of the disorders and that continued treatment with lithium seems to decrease this risk to the level of the general population.
Dr. Kessing has investigated the neurobiological basis of bipolar disorders as well as new treatment possibilities in a number of studies. During recent years he and his group have identified a number of potential biomarkers for bipolar disorder using innovative new clinical longitudinal study designs. Similarly, the use of Smartphones to generate objective behavioral markers of bipolar disorder has been investigated. He has, as the first, shown that early intervention in bipolar disorder improves long-term outcome with decreased risk of psychiatric hospitalization and improved adherence to medication and satisfaction with care.
He has received a number of prizes including the international NARSAD Bipolar Mood Disorder Prize for "Outstanding Achievement in Bipolar Mood Disorder Research" and the Travelling Professor Award for the Royal Australian and New Zealand College of Psychiatrists.
Dr. Kessing is the author of more than 290 peer reviewed scientific papers within affective disorders.
Kamilla Woznica Miskowiak, Psykolog
As senior research psychologist I lead the Neurocognition and Emotion in Affective Disorder (NEAD) Group at CADIC, which consists of a number of PhD students, MSc students, and BSc students. The NEAD Group aims to (1) identify neurocognitive and neuroimaging biomarkers of these affective disorders, (2) develop new biological and psychological treatments targeting cognitive dysfunction across the disorders and (3) delineate the neurocognitive and neuroimaging mechanisms of established and novel treatments. We conduct a number of clinical and experimental studies in patients with affective disorders using clinical ratings, neurocognitive testing and functional magnetic resonance imaging (fMRI). For details on the group members and ongoing projects, see www.psykiatri-regionh.dk/NEAD-Group. Alongside my research I have received training in and worked with cognitive behavioural therapy of patients with depression or bipolar disorder and qualified as clinical psychologist in 2011.
Anne Juul Bjertrup,BSc
Postgraduate student of psychology (University of Copenhagen) and research assistant.
I work on the HEAPAD study investigating emotional cognition in pregnant women with affective disorders.
My research interests lie in the field of neuropsychology and psychiatry.
Caroline Vintergaard Ott, Psykolog
I am a psychologist currently employed as a research assistant in the Neurocognition and Emotion in Affective Disorders (NEAD) Group. I start a PhD in December 2016 under supervision of Dr Kamilla Miskowiak, where I will carry out a cognitive remediation therapy (CRT) programme for patients with bipolar disorder in remission and healthy first-degree relatives.
My main research interests are novel psychological and pharmacological treatments of cognitive impairment across affective disorders, and the identification of biomarkers of cognitive impairment.
Klaus Martiny is founder and head of the NID group whose primary aim is to develop and test new interventions and treatments for depression.
The NID group works within the areas of pharmacology, neurostimulation, chronotherapeutics, sleep, behavior, and environmental factors (for current projects see under main scientific areas).
NID group: Klaus Martiny, PhD, DMSc, Clinical Associate Research Professor; Signe Dunker Svendsen, MHS; Anne Præstegaard, lab assistant; Carlo Volf, MAA, PhD; Philip Løventoft M.Sc.; Lasse Nørregaard M.Sc.; Kristin Evensen MSc student; Jonathan Jetsmark Bjerre.
Reserach assistent in the NEAD group
Signe Dunker Svendsen
Study nurse in the in the NEAD group
Specialist in psychiatry and Chief Physician, MD, DMSc.
Main research focus is pathophysiology of bipolar disorder and identification of biological markers.
MD, PhD, DMSc Clinical Associate Research Professor, University of Copenhagen and Senior Consultant, Psychiatric Centre Copenhagen.
Primary research goal:
To advance the present understanding of the complex biological, psychological and environmental interrelation underlying affective disorders to both prevent the development and halt the progression of these severe, potentially disabling disorders.
Overall scientific focus: electronic monitoring in bipolar disorder. Has investigated trait and state alterations in objectively measured psychomotor activity in patients with bipolar disorder for several years. Was a part of the development of the MONARCA system for smartphones. Conducted the MONARCA I trial investigating the effect of smartphone-based electronic self-monitoring in patients with bipolar disorder, as well as pilot studies using the MONARCA system. Are currently conducting the MONARCA II trial investigating the effect of smartphone-based monitoring in bipolar disorder. Is a work package leader in the Bipolar Illness Onset (BIO) study investigating the use of smartphone data as a biomarker in bipolar disorder. Is one of the principal investigators of the Next generation Mobile Platforms for HeAlth, in Mental Disorders (NYMPHA) study; the Reducing the rate and duration of Re-ADMISsions (RADMIS) trial; and the Technology Enabled Adolescent Mental Health (TEAM) study.
Medical doctor and PhD student (University of Copenhagen). I work on the NEAD project focusing on the biological biomarkers in affective disorders. I graduated as a medical doctor from the University of Copenhagen in 2012 with my thesis about the role of estrogen in bipolar disorder. My research interest is primarily the biological underpinnings of affective disorders.
|||Sharleny Stanislaus, MD|
Medical doctor and PhD student (University of Copenhagen). I am working on the bipolar illness onset study (BIO) that aims to identify and optimize a composite smartphone-based electronic marker by investigating smartphone data in patients with bipolar disorder, healthy relatives at risk and healthy control individuals. I graduated from the Medical University of Copenhagen in 2012 and I have gained clinical experience through internships in psychiatric hospitals.
Associates Clinical Research Professor at the University of Copenhagen, Senior Consultant at Psychiatric Center Copenhagen, PhD.
My scientific focus is the etiology of affective disorders addressed in clinical studies, systematic reviews and meta-analyses. Currently head of a prospective clinical study of cognition and biomarkers in cerebrospinal fluid; ABETA-study, along with a line of collaborations
|||Vibe G. Frøkjær|
Associated researchers: Vibe G. Frøkjær, MD, PhD, Senior researcher with responsibility for the Clinical Psychiatry section at Neurobiology Research Unit (hyperlink:
work package leader of the "Predicting Treatment Outcome in Major Depressive Disorder" project at NeuroPharm (hyperlink:
http://neuropharm.eu), and under clinical training in psychiatry at Mental Health Services Copenhagen. I (or Vibe) hold (s) an expertise in multimodal functional molecular brain imaging and steroid hormone biology in the context of risk and resilience to neruopsychiatric disorders, in particular mood disorders (if you want you can link to my publication list at: www.vibegf.dk).
|||Jeff Zarp Petersen|
Postgraduate student of psychology (University of Copenhagen) and research assistant in the NEAD Group, CADIC. After obtaining my MSc in spring 2017, I will begin my Ph.D. studies in the NEAD Group under the supervision of Dr. Kamilla Miskowiak.
As a research assistant, I assist with neurocognitive testing and ratings of participants in several ongoing projects, including the BIO and the NEAD studies. My research interests are cognitive deficits in depression, the underlying neuropathophysiology, and the relationship between psychological and neurobiological perspectives in understanding and treating affective disorders."
Study nurse. I work on the MONARCA II trial, concerning smartphone-based self-monitoring to patients with bipolar disorder.
My key research interest is to help find methods and treatments that can promote remission and quality of life of people with mental illness.
From March 2017 I will also work as a study nurse on the RADMIS trial.