Lars Vedel Kessing, MD, DMSc
Lars Vedel Kessing is the leader of the Copenhagen Affective Disorder research Center (CADIC). He has since 2002 been appointed as professor in psychiatry at the Psychiatric Center Copenhagen and the University Hospital of Copenhagen, Denmark.
Dr. Kessing's scientific contributions are within clinical, epidemiological and neurobiological research in bipolar and unipolar affective disorders.
His major achievements has been to show that the longitudinal course of illness in depressive disorder and in bipolar disorder on average is progressive in nature with increasing severity of depressive episodes, increasing risk of recurrence of depressive and manic episodes and with increasing prevalence of cognitive dysfunction with the number of affective episodes. Further, he has shown that the risk of developing dementia is increased compared to the general population, and that the risk seems to increase with progression of the disorders and that continued treatment with lithium seems to decrease this risk to the level of the general population.
Dr. Kessing has investigated the neurobiological basis of bipolar disorders as well as new treatment possibilities in a number of studies. During recent years he and his group have identified a number of potential biomarkers for bipolar disorder using innovative new clinical longitudinal study designs. Similarly, the use of Smartphones to generate objective behavioral markers of bipolar disorder has been investigated. He has, as the first, shown that early intervention in bipolar disorder improves long-term outcome with decreased risk of psychiatric hospitalization and improved adherence to medication and satisfaction with care.
He has received a number of prizes including the international NARSAD Bipolar Mood Disorder Prize for "Outstanding Achievement in Bipolar Mood Disorder Research" and the Travelling Professor Award for the Royal Australian and New Zealand College of Psychiatrists.
Dr. Kessing is the author of more than 480 peer reviewed scientific papers within affective disorders.
Martin Balslev Jørgensen, Professor, MD, DMSc
MBJ leads the Depression biology group aiming to elucidate the biology of depression, to establish the mechanisms of action and predictors of effect of treatment interventions such as ECT antidepressants and psychotherapy and disentangle it from the biology of comorbid disorders. We employ methods from animal experiments and clinical trials to register based epidemiological studies.
Kamilla Woznica Miskowiak, professor, clinical psychologist, DMSc, DPhil
Kamilla Woznica Miskowiak is the leader of the Neurocognition and Emotion in Affective Disorder (NEAD) Group at CADIC, which consists of a number of postdocs, PhD students, MSc students, and BSc students. The NEAD Group works on research into cognitive impairments and affective disorders (depression and bipolar disorder) and aims to: (1) Identify neurocognitive and neuroimaging biomarkers of unipolar and bipolar disorders, (2) Create neurocognitive screening tools and methods to reduce the risk of these affective disorders, (3) Develop new biological and psychological treatments targeting cognitive dysfunction and (4) Delineate the neurocognitive and neuronal mechanisms of established and novel treatments.
We conduct a number of clinical and experimental studies in patients with affective disorders using clinical ratings, neurocognitive testing and functional magnetic resonance imaging (fMRI). For details on the group members, ongoing projects and published papers from the group, see www.psykiatri-regionh.dk/NEAD-Group.
Klaus Martiny, professor, MD, PhD
Klaus Martiny is founder and head of the NID group whose primary aim is to develop and test new interventions and treatments for depression.
The NID group works within the areas of pharmacology, neurostimulation, chronotherapeutics, sleep, behavior, and environmental factors (for current projects see under main scientific areas).
Maj Vinberg, professor, MD, PhD, DMSc, University of Copenhagen and Psychiatric Centre Nordsjælland
Primary research goal: To advance the present understanding of the complex biological, psychological and environmental interrelation underlying affective disorders to both prevent the development and halt the progression of these severe, potentially disabling disorders.
Maria Faurholt-Jepsen MD, DMSc
Overall scientific focus: electronic monitoring in bipolar disorder. Has investigated trait and state alterations in objectively measured psychomotor activity in patients with bipolar disorder for several years. Was a part of the development of the MONARCA system for smartphones. Conducted the MONARCA I and II trials investigating the effect of smartphone-based electronic self-monitoring in patients with bipolar disorder. Is a work package leader in the Bipolar Illness Onset (BIO) study investigating the use of smartphone data as a biomarker in bipolar disorder. Was one of the principal investigators of the Next generation Mobile Platforms for HeAlth, in Mental Disorders (NYMPHA) study; the Reducing the rate and duration of Re-ADMISsions (RADMIS) trial; and the Technology Enabled Adolescent Mental Health (TEAM) study.
Anders Jørgensen MD, Associate Professor, Consultant, PhD
Main research areas are electroconvulsive therapy and molecular aging mechanisms in psychiatric disorders. Is currently working on establishing a research and quality database for ECT, as well as on several projects involving markers of nucleic acid damage from oxidative stress in psychiatric diseases and during treatment with psychotropic drugs.
Ulla Knorr, Senior Consultant at Psychiatric Center Copenhagen, PhD.
My scientific focus is the etiology of affective disorders addressed in clinical studies, systematic reviews and meta-analyses. Currently head of a prospective clinical study of cognition and biomarkers in cerebrospinal fluid; ABETA-study, along with a line of collaborations.
Vibe G. Frøkjær
Associated researchers: Vibe G. Frøkjær, MD, PhD, Senior researcher with responsibility for the Clinical Psychiatry section at Neurobiology Research Unit (hyperlink:
work package leader of the "Predicting Treatment Outcome in Major Depressive Disorder" project at NeuroPharm (hyperlink:
http://neuropharm.eu), and under clinical training in psychiatry at Mental Health Services Copenhagen. I (or Vibe) hold (s) an expertise in multimodal functional molecular brain imaging and steroid hormone biology in the context of risk and resilience to neruopsychiatric disorders, in particular mood disorders (if you want you can link to my publication list at: www.vibegf.dk).
Post doc researchers
MD, Phd Klara Coello
MSc psychology, PhD Hanne Lie Kjærstad
MD, PhD Katrine Maigaard
MD, PhD Sharleny Stanislaus
MD, PhD Morten Lindbjerg Tønning
MSc psychology, PhD Anne Juul Bjertrup
MSc psychology, PhD Jeff Zarp Petersen
Cand.scient.san. PhD, Frederikke Hørdam Gronemann
MD Caroline Fussing
MD Helle Krogh
MD Ida Kim Wium-Andersen
MD Julie Ravneberg Stokholm
MD Kristian Reveles Jensen